Transcranial | opira-avanaki

TRANSCRANIAL BRAIN IMAGING (STUDY THE EFFECT OF SKULL)

Skull bone represents a highly acoustical impedance mismatch and a dispersive barrier for the propagation of acoustic waves. Skull distorts the amplitude and phase information of the received waves at different frequencies in a transcranial brain imaging. We have studied the effect of the skull on the photoacoustic image formation in both the illumination path and acoustic propagation path separately and combined. We have developed algorithms for the compensation of the skull-induced distortions in transcranial photoacoustic tomography and microscopy. These algorithms have been tested on tissue phantoms and large animal skull tissues.

L. Mohammadi et al., “Skull’s Aberration Correction using Vector Space Similarity Model: A Proof-of-Concept Simulation Study”, Submitted (available upon request)
R. Manwar et al., “Skull Characterization with a Bioengineer Perspective: Application in Ultrasound and Photoacoustic Imaging”, In preparation (available upon request)
R. Manwar et al., “Investigation of the Effect of the Skull in Transcranial Photoacoustic Imaging: A Preliminary Ex Vivo Study”, Sensors 20 (15), 4189 (2020)
L. Mohammadi et al., “Skull’s aberration modeling: towards photoacoustic human brain imaging”, Photons Plus Ultrasound: Imaging and Sensing 10878, 108785W (2019)
L. Mohammadi et al., “Skull’s photoacoustic attenuation and dispersion modeling with deterministic ray-tracing: towards Real-time aberration correction”, Sensors 19 (2), 345 (2019)
L. Mohammadi et al., “Skull's acoustic attenuation and dispersion modeling on photoacoustic signal”, Photons Plus Ultrasound: Imaging and Sensing 2018 10494, 104946K (2018)
B. Volinski et al., “Photoacoustic investigation of a neonatal skull phantom”, Photons Plus Ultrasound: imaging and Sensing 2017 10064, 100643T (2017)
Q. Xu et al., “Effect of small and large animal skull bone on photoacoustic signal”, Photons Plus Ultrasound: Imaging and Sensing 2017 10064, 100643S (2017)
L. Mohammadi et al., “Modeling skull's acoustic attenuation and dispersion on photoacoustic signal”, Photons Plus Ultrasound: Imaging and Sensing 2017 10064, 100643U (2017)